2026

Long-read transcriptome assembly reveals vast transcriptional complexity in the placenta associated with metabolic and endocrine function
Long-read transcriptome assembly reveals vast transcriptional complexity in the placenta associated with metabolic and endocrine function

Sean T. Bresnahan, Hannah Yong, William H. Wu, Sierra Lopez, Jerry K. Y. Chan, Fergus White, Pierre-Étienne Jacques, Marie-France Hivert, Shiao-Yng Chan, Michael I. Love, Jonathan Y. Huang, Arjun Bhattacharya

Nature Communications 2026

Long-read transcriptome assembly reveals vast transcriptional complexity in the placenta associated with metabolic and endocrine function

Sean T. Bresnahan, Hannah Yong, William H. Wu, Sierra Lopez, Jerry K. Y. Chan, Fergus White, Pierre-Étienne Jacques, Marie-France Hivert, Shiao-Yng Chan, Michael I. Love, Jonathan Y. Huang, Arjun Bhattacharya

Nature Communications 2026

Natural variation in transplacental transfer efficiency exposes distinct transcriptional network architectures of PFAS effects on birth weight and gestational age
Natural variation in transplacental transfer efficiency exposes distinct transcriptional network architectures of PFAS effects on birth weight and gestational age

Sean T. Bresnahan, Hannah E. J. Yong, Martin G. Drelichman, Sarah N. Campbell, Anna E. Trapse, Gabriela R. Romo, Christina M. Cellini, Sierra Lopez, Jerry K. Yen Chan, Shiao-Yng Chan, Elana R. Elkin, Arjun Bhattacharya, Jonathan Y. Huang

bioRxiv 2026 ; in revision at Environmental Health Perspectives Preprint

Natural variation in transplacental transfer efficiency exposes distinct transcriptional network architectures of PFAS effects on birth weight and gestational age

Sean T. Bresnahan, Hannah E. J. Yong, Martin G. Drelichman, Sarah N. Campbell, Anna E. Trapse, Gabriela R. Romo, Christina M. Cellini, Sierra Lopez, Jerry K. Yen Chan, Shiao-Yng Chan, Elana R. Elkin, Arjun Bhattacharya, Jonathan Y. Huang

bioRxiv 2026 ; in revision at Environmental Health Perspectives Preprint

Improving isoform-level eQTL and integrative genetic analyses of breast cancer risk with long-read RNA transcript assemblies
Improving isoform-level eQTL and integrative genetic analyses of breast cancer risk with long-read RNA transcript assemblies

S. Taylor Head, Aryun Nemani, Yung-Han Chang, Tabitha A. Harrison, Sean T. Bresnahan, Joseph H. Rothstein, Weiva Sieh, Sara Lindström, Arjun Bhattacharya

bioRxiv 2026 ; in revision at Nature Genetics Preprint

Improving isoform-level eQTL and integrative genetic analyses of breast cancer risk with long-read RNA transcript assemblies

S. Taylor Head, Aryun Nemani, Yung-Han Chang, Tabitha A. Harrison, Sean T. Bresnahan, Joseph H. Rothstein, Weiva Sieh, Sara Lindström, Arjun Bhattacharya

bioRxiv 2026 ; in revision at Nature Genetics Preprint

2025

Quantification method affects replicability of eQTL analysis, colocalization, and TWAS
Quantification method affects replicability of eQTL analysis, colocalization, and TWAS

S. Taylor Head, Sean T. Bresnahan, Nolan Cole, William Wu, Arjun Bhattacharya

bioRxiv 2025 ; in revision at Nature Genetics Preprint

Quantification method affects replicability of eQTL analysis, colocalization, and TWAS

S. Taylor Head, Sean T. Bresnahan, Nolan Cole, William Wu, Arjun Bhattacharya

bioRxiv 2025 ; in revision at Nature Genetics Preprint

Intragenomic conflict associated with extreme phenotypic plasticity in queen-worker caste determination in honey bees (Apis mellifera)
Intragenomic conflict associated with extreme phenotypic plasticity in queen-worker caste determination in honey bees (Apis mellifera)

Sean T. Bresnahan, Shaun Mahony, Kate Anton, Brock Harpur, Christina M. Grozinger

Genome Biology, 26, 171. 2025

Intragenomic conflict associated with extreme phenotypic plasticity in queen-worker caste determination in honey bees (Apis mellifera)

Sean T. Bresnahan, Shaun Mahony, Kate Anton, Brock Harpur, Christina M. Grozinger

Genome Biology, 26, 171. 2025

Isoform-level analyses of 6 cancers uncover extensive genetic risk mechanisms undetected at the gene level
Isoform-level analyses of 6 cancers uncover extensive genetic risk mechanisms undetected at the gene level

Yung-Han Chang, Sean T. Bresnahan, S. Taylor Head, Tabitha Harrison, Yao Yu, Chad D. Huff, Bogdan Pasaniuc, Sara Lindström, Arjun Bhattacharya

British Journal of Cancer, 133, 874-885. 2025

Isoform-level analyses of 6 cancers uncover extensive genetic risk mechanisms undetected at the gene level

Yung-Han Chang, Sean T. Bresnahan, S. Taylor Head, Tabitha Harrison, Yao Yu, Chad D. Huff, Bogdan Pasaniuc, Sara Lindström, Arjun Bhattacharya

British Journal of Cancer, 133, 874-885. 2025

2023

Beyond conflict: Kinship theory of intragenomic conflict predicts individual variation in altruistic behaviour
Beyond conflict: Kinship theory of intragenomic conflict predicts individual variation in altruistic behaviour

Sean T. Bresnahan, David Galbraith, Rong Ma, Kate Anton, Juliana Rangel, Christina M. Grozinger

Molecular Ecology, 32, 5823-5837. 2023

Beyond conflict: Kinship theory of intragenomic conflict predicts individual variation in altruistic behaviour

Sean T. Bresnahan, David Galbraith, Rong Ma, Kate Anton, Juliana Rangel, Christina M. Grozinger

Molecular Ecology, 32, 5823-5837. 2023

More than mesolectic: Characterizing the nutritional niche of Osmia cornifrons
More than mesolectic: Characterizing the nutritional niche of Osmia cornifrons

Makaylee K. Crone, Natalie K. Boyle, Sean T. Bresnahan, David J. Biddinger, Rodney T. Richardson, Christina M. Grozinger

Ecology and Evolution, 13, e10640. 2023

More than mesolectic: Characterizing the nutritional niche of Osmia cornifrons

Makaylee K. Crone, Natalie K. Boyle, Sean T. Bresnahan, David J. Biddinger, Rodney T. Richardson, Christina M. Grozinger

Ecology and Evolution, 13, e10640. 2023

Examining parent-of-origin effects on transcription and RNA methylation in mediating aggressive behavior in honey bees (Apis mellifera)
Examining parent-of-origin effects on transcription and RNA methylation in mediating aggressive behavior in honey bees (Apis mellifera)

Sean T. Bresnahan, Ellen Lee, Lindsay Clark, Rong Ma, Michael Markey, Juliana Rangel, Christina M. Grozinger, Hongmei Li-Byarlay

BMC Genomics, 24, 315. 2023

Examining parent-of-origin effects on transcription and RNA methylation in mediating aggressive behavior in honey bees (Apis mellifera)

Sean T. Bresnahan, Ellen Lee, Lindsay Clark, Rong Ma, Michael Markey, Juliana Rangel, Christina M. Grozinger, Hongmei Li-Byarlay

BMC Genomics, 24, 315. 2023

2021

Tissue-specific transcriptional patterns underlie seasonal phenotypes in honey bees
Tissue-specific transcriptional patterns underlie seasonal phenotypes in honey bees

Sean T. Bresnahan, Mehmet A. Döke, Tugrul Giray, Christina M. Grozinger

Molecular Ecology, 31, 174-184. 2021

Tissue-specific transcriptional patterns underlie seasonal phenotypes in honey bees

Sean T. Bresnahan, Mehmet A. Döke, Tugrul Giray, Christina M. Grozinger

Molecular Ecology, 31, 174-184. 2021